Learn how Cymbalta can help treat or manage your symptoms. More

I have been prescribed Cymbalta for:

The Journey to Improvement

If you are concerned about some of your symptoms, here are a few important first steps on the journey to improvement:

1. Learn more about depression
Find out how depression affects you and read about the various treatments available before speaking with a healthcare professional. You can also make a list of questions to ask during your visit. View some questions to ask your doctor.

Cymbalta and depression

Treating depression with Cymbalta

2. Talk to your friends and family
Your loved ones can be a source of comfort and emotional support. They may even help you with practical things like finding a doctor or therapist. You don't have to face depression alone. After talking to friends and family about it, you might actually feel relieved.

3. Make an appointment with a doctor
Talk to your doctor or another healthcare professional about your symptoms. He or she can tell you whether you have depression and work with you to plan a course of action that you feel good about. Your doctor may also suggest that you see a specialist, such as a psychiatrist or a therapist. Learn more about different ways of treating depression.

A Note About Suicidal Thoughts

Thoughts about death or suicide are common in depression, and it's important to take such thoughts seriously. If you feel like giving up or as if you might hurt yourself, get help immediately:

If You Are Concerned About Some of Your Symptoms, Here Are Some Steps You Can Take to Help You Determine What You Need to Do Next



Cymbalta® (duloxetine HCl) is approved for the treatment of depression and generalized anxiety disorder, and for the management of diabetic peripheral neuropathic pain and fibromyalgia. What should I talk about with my healthcare provider? Patients on antidepressants and their families or caregivers should watch for new or worsening symptoms, unusual changes in behavior, thoughts of suicide, anxiety, agitation, panic attacks, difficulty sleeping, irritability, hostility, aggressiveness, impulsivity, restlessness, or extreme hyperactivity. Call your healthcare provider right away if you have thoughts of suicide or if any of these symptoms are severe or occur suddenly. Be especially observant within the first few months of antidepressant treatment or whenever there is a change in dose. You should also know that: Suicide is a known risk of depression and some other psychiatric disorders. Antidepressants may increase suicidal thoughts or behaviors in some children, adolescents, and young adults especially within the first few months of treatment or when changing the dose. No increased risk has been shown for adults over age 24, and risk decreased for those over age 65. All patients starting therapy should be monitored appropriately and observed closely for new or worsening depression symptoms, suicidal thoughts or behavior, or unusual changes in behavior. Cymbalta is not approved for use in patients under age 18. Who should NOT take Cymbalta? You should not take Cymbalta if: You have recently taken a type of antidepressant called a monoamine oxidase inhibitor (MAOI) You have uncontrolled narrow-angle glaucoma (an eye disease) You are taking Mellaril® (thioridazine) What other important information should I discuss with my healthcare provider? Before starting Cymbalta, tell your healthcare provider: about all of your medical conditions, including kidney problems, glaucoma, or diabetes about your alcohol use if you are taking nonprescription or prescription medicines, including those for migraine, to address a possible life-threatening condition if you are taking NSAID pain relievers, aspirin, or blood thinners. Use with Cymbalta may increase bleeding risk if you are pregnant, plan to become pregnant during therapy, or are breastfeeding an infant While taking Cymbalta, tell your healthcare provider: if you have itching, right upper belly pain, dark urine, yellow skin/eyes, or unexplained flu-like symptoms, which may be signs of liver problems. Severe liver problems, sometimes fatal, have been reported if you have high fever, confusion, and stiff muscles to address a possible life-threatening condition before stopping Cymbalta or changing your dose if you experience dizziness or fainting upon standing, especially when first starting Cymbalta or when increasing the dose. Your healthcare provider may periodically check your blood pressure while you are taking Cymbalta If you have any questions, talk to your healthcare provider before taking Cymbalta. What are the possible side effects of Cymbalta? The most common side effect of Cymbalta was nausea. For most people who had it, the nausea was mild to moderate. Other common side effects included dry mouth, sleepiness, constipation, decreased appetite, and increased sweating. This is not a complete list of side effects. Please read additional Safety Information and Boxed Warning for a complete list.
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